Reversible protonation of a thiolate ligand in an [Fe]-hydrogenase model complex

The thiolate ligand in the five-coordinate model complex 1 of [Fe]-hydrogenase is preferentially and reversibly protonated, even in the presence of an acyl ligand. The results suggest that the Cys176 thiolate ligand in [Fe]-hydrogenase can serve as the internal base to accept the proton after heterolytic splitting of H2.


Published in:
Angewandte Chemie International Edition, 51, 8, 1919-1921
Year:
2012
Keywords:
Laboratories:




 Record created 2012-02-15, last modified 2018-03-17


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