Magnetic Particle Handling In Microfluidic Systems

We present techniques and methodologies for the manipulation of magnetic micro- and nanoparticles ('beads') in microfluidic systems. We first introduce the most important forces that act on magnetic particles in a microfluidic system. Starting with the magnetic force that is responsible for the primary actuation of the magnetic particles, we discuss the viscous drag force induced when the particles are moving with a speed different from the liquid in the microfluidic channel. These forces can be combined in time and space to realize the basic manipulation steps of magnetic beads in a microfluidic system: retention, separation, mixing and transport. We also discuss the use of beads as magnetic detection labels or as magnetic force mediators inside droplets.


Published in:
Microfluidics Based Microsystems: Fundamentals And Applications, 467-480
Presented at:
Conference of the NATO-Advanced-Study-Institute on Microfluidics Based Microsystems - Fundamentals and Applications, Cesme Izmir, TURKEY, Aug 23-Sep 04, 2009
Year:
2010
Publisher:
Springer, 101 Philip Drive, Norwell, Ma 02061 Usa
ISBN:
978-90-481-9028-7
Keywords:
Laboratories:




 Record created 2012-01-12, last modified 2018-03-17


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