Maleimide-functionalised organoruthenium anticancer agents and their binding to thiol-containing biomolecules
Hanif, Muhammad; Nazarov, Alexey A.; Legin, Anton; Groessl, Michael; Arion, Vladimir B.; Jakupec, Michael A.; Tsybin, Yury O.; Dyson, Paul J.; Keppler, Bernhard K.; Hartinger, Christian G.
2012

Abstract

Ru-II(arene) anticancer compounds with maleimide functionality were prepared to allow selective interaction with thiol-containing biomolecules and thereby enforcing the selective delivery of the compounds to the tumour.

Details

Title Maleimide-functionalised organoruthenium anticancer agents and their binding to thiol-containing biomolecules
Author(s) Hanif, Muhammad ; Nazarov, Alexey A. ; Legin, Anton ; Groessl, Michael ; Arion, Vladimir B. ; Jakupec, Michael A. ; Tsybin, Yury O. ; Dyson, Paul J. ; Keppler, Bernhard K. ; Hartinger, Christian G.
Published in Chemical Communications
Volume 48
Issue 10
Pages 1475
Date 2012
ISSN 1364-548X
Keywords
DOI https://doi.org/10.1039/c1cc14713g
Other identifier(s) View record in Web of Science
Laboratories LSMB
LCOM
Record Appears in Scientific production and competences > SB - School of Basic Sciences > ISIC - Institute of Chemical Sciences and Engineering > LCOM - Laboratory of Organometallic and Medicinal Chemistry
Scientific production and competences > SB - School of Basic Sciences > SB Archives > LSMB - Biomolecular Mass Spectrometry Laboratory
Peer-reviewed publications
Work produced at EPFL
Journal Articles
Published
Record creation date 2012-01-12

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