Colossal magnetoresistance (CMR) and colossal electroresistance (CER) induced by the electric field in spinel multiferroic CdCr2S4 are reported. It is found that a metal-insulator transition in CdCr2S4 is triggered by the electrical field. In magnetic fields, the resistivity rho of CdCr2S4 responds similarly to that of CMR manganites. Combing previous reports, these findings make CdCr2S4 the unique compound to possess all four properties of the colossal magnetocapacitive, colossal electrocapacitive, CER, and CMR. The present results open a new venue for searching new materials to show CMR by tuning electric and magnetic fields.