000172759 001__ 172759
000172759 005__ 20180913061024.0
000172759 0247_ $$2doi$$a10.1016/j.apradiso.2009.09.042
000172759 02470 $$2ISI$$a000276418600063
000172759 037__ $$aCONF
000172759 245__ $$aX-ray phase contrast imaging of the bone-cartilage interface
000172759 260__ $$c2010
000172759 269__ $$a2010
000172759 336__ $$aConference Papers
000172759 520__ $$aSynoyial joints articulate in a lubricating environment, the system providing for smooth articulation. The articular cartilage overlying the bone consists of a network of collagen fibres. This network is essential to cartilage integrity, suffering damage in degenerative joint disease such as osteoarthritis. At Surrey and also in work conducted by this group at the Paul Scherrer Institute (PSI) synchrotron site we have been applying a number of techniques to study the bone-cartilage interface and of changes occurring in this with disease. One of the techniques attracting particular interest is X-ray phase contrast imaging, yielding information on anatomical features that manifest from the large scale organisation of collagen and the mineralised phase contained within the collagen fibres in the deep cartilage zone. This work briefly reviews some of the basic supporting physics of X-ray phase contrast imaging and then shows example images of the articular surface and subchondral bone and other supporting results obtained to-date. Present results have been obtained on sections of bone not displaying evidence of an osteoarthritic lesion and can be used as a baseline against which diseased bone can be compared. (c) 2009 Elsevier Ltd. All rights reserved.
000172759 6531_ $$aX-rays
000172759 6531_ $$aPhase-contrast imaging
000172759 6531_ $$aCartilage
000172759 6531_ $$aOsteoarthritis
000172759 700__ $$aIsmail, Elna Che$$uUniv Surrey, Dept Phys, Guildford GU2 7XH, Surrey, England
000172759 700__ $$aKaabar, W.$$uUniv Surrey, Dept Phys, Guildford GU2 7XH, Surrey, England
000172759 700__ $$aGarrity, D.$$uUniv Surrey, Dept Phys, Guildford GU2 7XH, Surrey, England
000172759 700__ $$aGundogdu, O.$$uUniv Surrey, Dept Phys, Guildford GU2 7XH, Surrey, England
000172759 700__ $$aBunk, O.$$uPaul Scherrer Inst, CH-5232 Villigen, Switzerland
000172759 700__ $$0240201$$aPfeiffer, F.$$g181576$$uPaul Scherrer Inst, CH-5232 Villigen, Switzerland
000172759 700__ $$aFarquharson, M. J.$$uCity Univ London, Dept Radiog, London EC1V OHB, England
000172759 700__ $$aBradley, D. A.$$uUniv Surrey, Dept Phys, Guildford GU2 7XH, Surrey, England
000172759 7112_ $$a7th International Topical Meeting on Industrial Radiation and Radioisotope Measurement Application$$cPrague, CZECH REPUBLIC$$dJun 22-27, 2008
000172759 773__ $$j68$$q767-771$$tApplied Radiation And Isotopes
000172759 909C0 $$0252063$$pLSXC
000172759 909CO $$ooai:infoscience.tind.io:172759$$pconf
000172759 937__ $$aEPFL-CONF-172759
000172759 973__ $$aEPFL$$sPUBLISHED
000172759 980__ $$aCONF