In vivo labelling of resting monocytes in the reticuloendothelial system with fluorescent iron oxide nanoparticles prior to injury reveals that they are mobilized to infarcted myocardium
To evaluate the feasibility of loading resting monocytes/macrophages by intravenous (i.v.) injection of fluorescent iron oxide nanoparticles prior to injury and tracking of these cells in the very same animal to myocardial infarction (MI) by magnetic resonance imaging (MRI) and optical imaging.
Keywords: Magnetic resonance imaging ; Iron oxide nanoparticles ; Inflammation ; Myocardial infarction ; Chemoattractant Protein-1 ; Inflammatory Response ; Cell-Function ; Rat-Heart ; Mri ; Chemokines ; Tracking ; Agents ; Vitro ; Cine
Record created on 2011-12-16, modified on 2016-08-09