Electrochemical reactions and ionization processes
Electrochemical or photo-electrochemical reactions in both electrospray ionization and laser desorption ionization are discussed stressing the role of the electrode reaction in influencing the ionization process. In particular, upon application of a high voltage during electrospray ionization, the emitter includes a working electrode, where redox reactions are observed, such as electro-generation of benzoquinone and metal ions. In contrast, the target plate in laser-induced desorption ionization also acts as a photo-electrode, especially when modified with a mesoporous semiconductor. We illustrate here how these electrochemical reactions can be used for tagging purposes and for oxidative or reductive dissociation reactions.
Keywords: electrospray ionization ; emitters ; Ldi ; titanium dioxide nanoparticle ; semiconductor ; peptide in-source-decay ; cysteine tagging ; proteomics ; Electron Detachment Dissociation ; Microspray Mass-Spectrometry ; Laser-Desorption/Ionization ; Protein Identification ; Desorption-Ionization ; Cysteine Residues ; Disulfide Bonds ; Peptides ; Fragmentation ; Matrix
Record created on 2011-12-16, modified on 2016-08-09