Decaprenylphosphoryl-beta-D-Ribose 2 '-Epimerase from Mycobacterium tuberculosis is a Magic Drug Target
2010
Abstract
Tuberculosis is still a leading cause of death in developing countries and a resurgent disease in developed countries. The selection and soaring spread of Mycobacterium tuberculosis multidrug-resistant (MDR-TB) and extensively drug-resistant strains (XDR-TB) is a severe public health problem. Currently, there is an urgent need of new drugs for tuberculosis treatment, with novel mechanisms of action and, moreover, the necessity to identify new drug targets.
Details
Title
Decaprenylphosphoryl-beta-D-Ribose 2 '-Epimerase from Mycobacterium tuberculosis is a Magic Drug Target
Author(s)
Manina, G. ; Pasca, M. R. ; Buroni, S. ; De Rossi, E. ; Riccardi, G.
Published in
Current Medicinal Chemistry
Volume
17
Pages
3099-3108
Date
2010
Keywords
Other identifier(s)
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Laboratories
UPKIN
Record Appears in
Scientific production and competences > SV - School of Life Sciences > GHI - Global Health Institute > UPKIN - Prof. McKinney Group
Work produced at EPFL
Published
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Work produced at EPFL
Published
Reviews
Record creation date
2011-12-16