Synthesis of new oxathiazinane dioxides and their in vitro cancer cell growth inhibitory activity
2010
Abstract
New oxathiazinane dioxides have been derived from D- and L-serine and tested for their in vitro cell growth inhibitory activity toward SKBR3 breast cancer cells. (5R)-5-(4-(4'-Bromomethyl)phenyl)benzyloxymethyl-[1,3,4]-oxathiazinane- 3,3-dioxide showed a cytotoxicity of IC50 approximate to 10 mu M. (C) 2009 Elsevier Ltd. All rights reserved.
Details
Title
Synthesis of new oxathiazinane dioxides and their in vitro cancer cell growth inhibitory activity
Author(s)
Borcard, Francoise ; Baud, Matthias ; Bello, Claudia ; Dal Bello, Giovanna ; Grossi, Francesco ; Pronzato, Paolo ; Cea, Michele ; Nencioni, Alessio ; Vogel, Pierre
Published in
Bioorganic & Medicinal Chemistry Letters
Volume
20
Pages
5353-5356
Date
2010
Keywords
Other identifier(s)
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Laboratories
LGSA
Record Appears in
Scientific production and competences > SB - School of Basic Sciences > SB Archives > LGSA - Laboratory of Glycochemistry and Asymmetric Synthesis
Peer-reviewed publications
Work produced at EPFL
Journal Articles
Published
Peer-reviewed publications
Work produced at EPFL
Journal Articles
Published
Record creation date
2011-12-16