Parkinson-related parkin reduces α-Synuclein phosphorylation in a gene transfer model
Khandelwal, Preeti J.; Dumanis, Sonya B.; Feng, Li Rebekah; Maguire-Zeiss, Kathleen; Rebeck, Gw; Lashuel, Hilal A.; Moussa, Charbel Eh
2010

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Abstract

α-Synuclein aggregates in Lewy bodies and plays a central role in the pathogenesis of a group of neurodegenerative disorders, known as "Synucleinopathies", including Parkinson's disease. Parkin mutations result in loss of parkin E3-ubiquitin ligase activity and cause autosomal recessive early onset parkinsonism.

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Title Parkinson-related parkin reduces α-Synuclein phosphorylation in a gene transfer model
Author(s) Khandelwal, Preeti J. ; Dumanis, Sonya B. ; Feng, Li Rebekah ; Maguire-Zeiss, Kathleen ; Rebeck, Gw ; Lashuel, Hilal A. ; Moussa, Charbel Eh
Published in Molecular neurodegeneration
Volume 5
Pages 47
Date 2010
ISSN 1750-1326
DOI https://doi.org/10.1186/1750-1326-5-47
Other identifier(s) View record in Web of Science
Laboratories LMNN
Record Appears in Scientific production and competences > SV - School of Life Sciences > BMI - Brain Mind Institute > LMNN - Laboratory of Molecular Neurobiology and Neuroproteomics
Peer-reviewed publications
Work produced at EPFL
Journal Articles
Published
Record creation date 2011-12-16

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