Preparation of 5-Membered Rings via Radical Addition-Translocation-Cyclization (RATC) Processes Mediated by Diethyl Thiophosphites
2011
Abstract
A practical method for the formation of thiophosphonates bearing functionalized monocyclic, fused bicyclic and spirocyclic residues is presented. The procedure requires the easily available terminal alkynes as starting materials as well as commercially and readily available reagents such as diethyl thiophosphite. The experimental procedure consists of a one-pot process without any slow addition of one of the reagents.
Details
Title
Preparation of 5-Membered Rings via Radical Addition-Translocation-Cyclization (RATC) Processes Mediated by Diethyl Thiophosphites
Author(s)
Lamarque, Christophe ; Beaufils, Florent ; Denes, Fabrice ; Schenk, Kurt ; Renaud, Philippe
Published in
Advanced Synthesis & Catalysis
Volume
353
Pages
1353-1358
Date
2011
Keywords
alkynes; dialkyl phosphites; dialkyl thiophosphites; 1,5-hydrogen transfer; radical initiators; radical reactions; Phosphorus-Centered Radicals; Hydrogen-Atom Abstraction; Emmons-Type Reactions; Tin-Free Procedure; Cyclopentane Derivatives; Homolytic Substitution; 1,5-Hydrogen Transfer; Dialkyl Phosphites; Vinyl Radicals; Dienes
Other identifier(s)
View record in Web of Science
Laboratories
LCR
Record Appears in
Scientific production and competences > SB - School of Basic Sciences > IPHYS - Institute of Physics > LCR - Laboratory of Cristallography
Peer-reviewed publications
Work produced at EPFL
Journal Articles
Published
Peer-reviewed publications
Work produced at EPFL
Journal Articles
Published
Record creation date
2011-12-16