Preparation of 5-Membered Rings via Radical Addition-Translocation-Cyclization (RATC) Processes Mediated by Diethyl Thiophosphites

A practical method for the formation of thiophosphonates bearing functionalized monocyclic, fused bicyclic and spirocyclic residues is presented. The procedure requires the easily available terminal alkynes as starting materials as well as commercially and readily available reagents such as diethyl thiophosphite. The experimental procedure consists of a one-pot process without any slow addition of one of the reagents.


Published in:
Advanced Synthesis & Catalysis, 353, 1353-1358
Year:
2011
Keywords:
Laboratories:




 Record created 2011-12-16, last modified 2018-01-28


Rate this document:

Rate this document:
1
2
3
 
(Not yet reviewed)