Altered Expression of the Transcription Factor Mef2c during Retinal Degeneration in Rpe65(-/-) Mice

PURPOSE. To investigate the role of the myocyte enhancer factor 2 (Mef2) transcription factor family in retinal diseases, Mef2c expression was assessed during retinal degeneration in the Rpe65(-/-) mouse model of Leber's congenital amaurosis (LCA). Mef2c-dependent expression of photoreceptor-specific genes was further addressed.


Published in:
Investigative Ophthalmology & Visual Science, 52, 5933-5940
Year:
2011
Keywords:
Laboratories:




 Record created 2011-12-16, last modified 2018-09-13


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