Interference between PARPs and SIRT1: a novel approach to healthy ageing?
2011
Abstract
Poly(ADP-ribosyl) polymerases (PARPs) have traditionally been linked to chromosome maintenance and DNA repair. Recent findings identify PARPs as key modulators of metabolism through their influence on SIRT1 activity, hinting to a possible role of PARPs as longevity regulators.
Details
Title
Interference between PARPs and SIRT1: a novel approach to healthy ageing?
Author(s)
Cantó, Carles ; Auwerx, Johan
Published in
Aging
Volume
3
Issue
5
Pages
543-547
Date
2011
ISSN
1945-4589
Keywords
Other identifier(s)
View record in Web of Science
Laboratories
NCEM
Record Appears in
Scientific production and competences > SV - School of Life Sciences > IBI-SV - Interfaculty Institute of Bioengineering > NCEM - Nestlé Chair in Energy Metabolism
Peer-reviewed publications
Work produced at EPFL
Published
Reviews
Peer-reviewed publications
Work produced at EPFL
Published
Reviews
Record creation date
2011-11-15