000169410 001__ 169410
000169410 005__ 20180317093404.0
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000169410 013__ $$aAU2005306186$$bAU$$cB2$$d20120531
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000169410 013__ $$aEP1829893$$bEP$$cB1$$d20110921
000169410 013__ $$aMA29044$$bMA$$cB1$$d20071101
000169410 013__ $$aEP1829893$$bEP$$cA1$$d20070905
000169410 013__ $$aMX2007005808$$bMX$$cA$$d20070720
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000169410 013__ $$aAU2005306186$$bAU$$cA1$$d20060526
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000169410 02470 $$2EPO Family ID$$a40122436
000169410 037__ $$aPATENT
000169410 245__ $$aInterleukin 2 immune response generating formulation, used for treating cancer, comprises IL 2 coupled to transport protein, monoclonal anti IL 2 antibody or monoclonal anti CD 25 antibody
000169410 260__ $$c2006
000169410 269__ $$a2006
000169410 336__ $$aPatents
000169410 520__ $$aNOVELTY - A formulation comprising one or more components chosen from interleukin (IL)-2 or a derivative thereof coupled to a transport protein, a monoclonal anti-IL-2 antibody, a cancer vaccine based on specific antigens of tumors or tumor growth factors or a monoclonal anti-CD25 antibody, is new.  USE - The formulations are used to produce drugs for inducing an anti-IL-2 immune response capable of inhibiting the growth of tumors in cancer patients (claimed).  ADVANTAGE - Auto-antibodies which block binding of IL-2 to its receptor are induced and inhibit tumor growth.  DETAILED DESCRIPTION - A therapeutic formulation capable of generating an immune response to Interleukin 2 (IL-2), used for treating cancer patients, comprises at least one component chosen from:  (a) IL-2 or a derivative thereof coupled to a transport protein genetically or by chemical bonding, as well as a suitable adjuvant;  (b) a monoclonal anti-IL-2 antibody;  (c) a cancer vaccine based on specific antigens of tumors or tumor growth factors; or  (d) a monoclonal anti-CD25 antibody.
000169410 700__ $$aMONTERO CASIMIRO, J. E.
000169410 700__ $$aALONSO SARDUY, L. B.
000169410 700__ $$aPEREZ RODRIGUEZ, R.
000169410 700__ $$aLAGE DAVILA, A. B.
000169410 909C0 $$0252442$$pIPSB$$xU11993
000169410 917Z8 $$x182967
000169410 917Z8 $$x148230
000169410 937__ $$aEPFL-PATENT-169410
000169410 973__ $$aEPFL$$sPUBLISHED
000169410 980__ $$aPATENT