000168753 001__ 168753
000168753 005__ 20181203022441.0
000168753 037__ $$aARTICLE
000168753 245__ $$aAdhesion of Pseudomonas aeruginosa strains to untreated and oxygen-plasma treated poly(vinyl chloride) (PVC) from endotracheal intubation devices
000168753 260__ $$c2003
000168753 269__ $$a2003
000168753 336__ $$aJournal Articles
000168753 520__ $$aPseudomonas aeruginosa pneumonia is a life threatening complication in mechanically ventilated patients that requires the ability of the bacteria to adhere to, and colonize the endotracheal intubation device. New strategies to prevent or reduce these nosocomial infections are greatly needed. We report here the study of a set of P. aeruginosa clinical isolates, together with specific mutants, regarding their adhesion on native and chemically modified poly(vinyl chloride) (PVC) surfaces from endotracheal intubation devices. The adhesion of the different strains to untreated PVC varied widely, correlating with several physico-chemical characteristics known to influence the attachment of bacteria to inert surfaces. The adhesion patterns were compared to the calculations obtained with the DLVO theory of colloidal stability. These results illustrate the importance of testing different clinical isolates when investigating bacterial adhesion. Oxygen plasma treatment of the PVC pieces yielded a hydrophilic surface and reduced the number of adhering bacteria by as much as 70%. This reduction is however unlikely to be sufficient to prevent P. aeruginosa colonization of endotracheal intubation devices. (C) 2002 Elsevier Science Ltd. All rights reserved.
000168753 6531_ $$aPseudomonas aeruginosa
000168753 6531_ $$aclinical isolates
000168753 6531_ $$abiomedical PVC
000168753 6531_ $$aadhesion
000168753 6531_ $$asurface modification
000168753 6531_ $$aoxygen plasma
000168753 6531_ $$aphysico-chemical characterization
000168753 6531_ $$aVentilator-Associated Pneumonia
000168753 6531_ $$aTracheal Tube Biofilm
000168753 6531_ $$aBacterial Adhesion
000168753 6531_ $$aCell-Surface
000168753 6531_ $$aBand Lipopolysaccharide
000168753 6531_ $$aNosocomial Pneumonia
000168753 6531_ $$aPhysico-Chemistry
000168753 6531_ $$aA-Band
000168753 6531_ $$aElectrophoresis
000168753 6531_ $$aHydrophobicity
000168753 700__ $$aBalazs, D. J.
000168753 700__ $$aAronsson, B. O.
000168753 700__ $$aDescouts, P.
000168753 700__ $$aQuoc, P. T.
000168753 700__ $$avan Delden, C.
000168753 700__ $$aMathieu, H. J.
000168753 700__ $$0241276$$g120925$$aHarms, Hauke
000168753 700__ $$aTriandafillu, K.
000168753 773__ $$j24$$tBiomaterials$$q1507-1518
000168753 909C0 $$0252382$$pLPE
000168753 909CO $$particle$$ooai:infoscience.tind.io:168753
000168753 917Z8 $$x173008
000168753 937__ $$aEPFL-ARTICLE-168753
000168753 973__ $$rREVIEWED$$sPUBLISHED$$aEPFL
000168753 980__ $$aARTICLE