Phosphoric Acid-Catalyzed Enantioselective Transfer Hydrogenation of N-Aryl-ortho-Hydroxybenzophenone Ketimines
2011
Abstract
The first enantioselective chiral phosphoric acid-catalyzed transfer hydrogenation of N-aryl-ortho-hydroxybenzophenone ketimines using a Hantzsch ester as hydrogen source was developed to afford, after removal of the N-aryl group, the corresponding chiral diarylmethylamines in high yields and enantioselectivities.
Details
Title
Phosphoric Acid-Catalyzed Enantioselective Transfer Hydrogenation of N-Aryl-ortho-Hydroxybenzophenone Ketimines
Author(s)
Nguyen, Thanh Binh ; Bousserouel, Hadjira ; Wang, Qian ; Guéritte, Françoise
Published in
Advanced Synthesis & Catalysis
Volume
353
Issue
2-3
Pages
257-262
Date
2011
Publisher
Wiley-Blackwell
ISSN
1615-4150
Keywords
diarylmethylamines; Hantzsch esters; ortho-hydroxybenzophenone ketimine; organocatalysis; phosphoric acids; transfer hydrogenation; Chiral Bronsted Acid; Alpha-Imino Esters; Organocatalytic Transfer Hydrogenation; Asymmetric Transfer Hydrogenation; Friedel-Crafts Reaction; Organometallic Reagents; Kinetic Resolution; Arylboronic Acids; 3-Component Reaction; Reductive Amination
Other identifier(s)
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Laboratories
LSPN
Record Appears in
Scientific production and competences > SB - School of Basic Sciences > ISIC - Institute of Chemical Sciences and Engineering > LSPN - Laboratory of synthesis and natural products
Work produced at EPFL
Journal Articles
Published
Work produced at EPFL
Journal Articles
Published
Record creation date
2011-08-31