Heteroatom-Nucleophile-Induced C-C Fragmentations: Synthesis of Allenes and Entry to Domino Reactions
Saget, Tanguy; Cramer, Nicolai
2010

Abstract

Heteroatom nucleophiles (NuH) induce Grob-type fragmentations of cyclic vinyl triflates under mild conditions and provide ω-allene-functionalized carboxylic acid derivs. These products are a versatile starting point for domino and one-pot reactions accessing a range of structurally diverse scaffolds in good yields.

Details

Title Heteroatom-Nucleophile-Induced C-C Fragmentations: Synthesis of Allenes and Entry to Domino Reactions
Author(s) Saget, Tanguy ; Cramer, Nicolai
Published in Angewandte Chemie, International Edition
Volume 49
Pages 8962-8965
Date 2010
Publisher Wiley-VCH Verlag GmbH & Co. KGaA
ISSN 1433-7851
Keywords
Note CAPLUS AN 2010:1415419(Journal)
DOI https://doi.org/10.1002/anie.201004795
Laboratories LCSA
Record Appears in Scientific production and competences > SB - School of Basic Sciences > ISIC - Institute of Chemical Sciences and Engineering > LCSA - Laboratory of Asymmetric Catalysis and Synthesis
Peer-reviewed publications
Work outside EPFL
Journal Articles
Published
Record creation date 2011-08-17

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