Journal article

Heteroatom-Nucleophile-Induced C-C Fragmentations: Synthesis of Allenes and Entry to Domino Reactions

Heteroatom nucleophiles (NuH) induce Grob-type fragmentations of cyclic vinyl triflates under mild conditions and provide ω-allene-functionalized carboxylic acid derivs. These products are a versatile starting point for domino and one-pot reactions accessing a range of structurally diverse scaffolds in good yields.


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EPFL authors