Heteroatom-Nucleophile-Induced C-C Fragmentations: Synthesis of Allenes and Entry to Domino Reactions
Heteroatom nucleophiles (NuH) induce Grob-type fragmentations of cyclic vinyl triflates under mild conditions and provide œâ-allene-functionalized carboxylic acid derivs. These products are a versatile starting point for domino and one-pot reactions accessing a range of structurally diverse scaffolds in good yields.
CAPLUS AN 2010:1415419(Journal)
Record created on 2011-08-17, modified on 2016-08-09