Heteroatom-Nucleophile-Induced C-C Fragmentations: Synthesis of Allenes and Entry to Domino Reactions

Heteroatom nucleophiles (NuH) induce Grob-type fragmentations of cyclic vinyl triflates under mild conditions and provide ω-allene-functionalized carboxylic acid derivs. These products are a versatile starting point for domino and one-pot reactions accessing a range of structurally diverse scaffolds in good yields.


Published in:
Angewandte Chemie, International Edition, 49, 8962-8965, S8962/1-S8962/57
Year:
2010
Publisher:
Wiley-VCH Verlag GmbH & Co. KGaA
ISSN:
1433-7851
Keywords:
Note:
CAPLUS AN 2010:1415419(Journal)
Laboratories:




 Record created 2011-08-17, last modified 2018-03-17


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