Heteroatom-Nucleophile-Induced C-C Fragmentations: Synthesis of Allenes and Entry to Domino Reactions
2010
Abstract
Heteroatom nucleophiles (NuH) induce Grob-type fragmentations of cyclic vinyl triflates under mild conditions and provide ω-allene-functionalized carboxylic acid derivs. These products are a versatile starting point for domino and one-pot reactions accessing a range of structurally diverse scaffolds in good yields.
Details
Title
Heteroatom-Nucleophile-Induced C-C Fragmentations: Synthesis of Allenes and Entry to Domino Reactions
Author(s)
Saget, Tanguy ; Cramer, Nicolai
Published in
Angewandte Chemie, International Edition
Volume
49
Pages
8962-8965
Date
2010
Publisher
Wiley-VCH Verlag GmbH & Co. KGaA
ISSN
1433-7851
Keywords
Note
CAPLUS AN 2010:1415419(Journal)
Laboratories
LCSA
Record Appears in
Scientific production and competences > SB - School of Basic Sciences > ISIC - Institute of Chemical Sciences and Engineering > LCSA - Laboratory of Asymmetric Catalysis and Synthesis
Peer-reviewed publications
Work outside EPFL
Journal Articles
Published
Peer-reviewed publications
Work outside EPFL
Journal Articles
Published
Record creation date
2011-08-17