Beta-carbon elimination from cyclobutanols: a clean access to alkylrhodium intermediates bearing a quaternary stereogenic center

A review. The catalytic activation of C-C bonds bears significant ecol. and economical advantages. In this account, the authors describe their results for an enantioselective C-C activation of sym. substituted tert-cyclobutanols. Subsequent downstream reactions of the obtained alkylrhodium intermediate give rise to a wide range of synthetically versatile products bearing all-carbon quaternary stereogenic centers with excellent enantioselectivities.


Published in:
Synlett, 449-460
Year:
2011
Publisher:
Georg Thieme Verlag
ISSN:
0936-5214
Keywords:
Note:
CAPLUS AN 2011:465168(Journal; General Review)
Laboratories:




 Record created 2011-08-17, last modified 2018-03-17


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