Highly selective rhodium catalyzed domino C-H activation/cyclizations

The direct functionalization of carbon-hydrogen bonds is an emerging tool to establish more sustainable and efficient synthetic methods. We present its implementation in a cascade reaction that provides a rapid assembly of functionalized indanylamines from simple and readily available starting materials. Careful choice of the ancillary ligand - an electron-rich bidentate phosphine ligand - enables highly diastereoselective rhodium(I)-catalyzed intramol. allylations of unsubstituted ketimines induced by a directed C-H bond activation and allene carbo-metalation sequence.


Published in:
Chimia, 65, 271-273
Year:
2011
Publisher:
Swiss Chemical Society
ISSN:
0009-4293
Keywords:
Note:
CAPLUS AN 2011:677119(Journal)
Laboratories:




 Record created 2011-08-17, last modified 2018-03-17


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