Ni-catalyzed cross coupling of non-activated alkyl halides: a mechanistic perspective

Cross coupling of non-activated alkyl halides is a potentially transformative methodology in organic synthesis. Herein we review the recent development of nickel-catalyzed coupling of non-activated alkyl halides. The current understanding of the mechanism of these coupling reactions is highlighted. As the mechanism is ligand-dependant, the perspective is organized according to the types of ligands employed in the catalysis.


Published in:
Chemical Science, 2, 1867-1886
Year:
2011
Laboratories:




 Record created 2011-07-22, last modified 2018-03-17


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