Infoscience

Journal article

Two-Photon Excited Fluorescence Enhancement for Ultrasensitive DNA Detection on Large-Area Gold Nanopatterns

Ultrasensitive DNA detection using enhanced two-photon excited fluorescence: DNA detection systems formed on a highly regular gold nanopattern over a large area show enhanced sensitivity from high to ultralow concentrations (similar to 10-11 M, see figure) target molecules. The observed two-photon excited fluorescence on the gold patterned surface is enhanced over two orders of magnitude compared with the molecules on the glass surface.

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