Common human genetic variants and HIV-1 susceptibility: a genome-wide survey in a homogeneous African population
Petrovski, Slavé; Fellay, Jacques; Shianna, Kevin V.; Carpenetti, Nicole; Kumwenda, Johnstone; Kamanga, Gift; Kamwendo, Deborah D.; Letvin, Norman L.; McMichael, Andrew J.; Haynes, Barton F.; Cohen, Myron S.; Goldstein, David B.
2011

Abstract

To date, CCR5 variants remain the only human genetic factors to be confirmed to impact HIV-1 acquisition. However, protective CCR5 variants are largely absent in African populations, in which sporadic resistance to HIV-1 infection is still unexplained. We investigated whether common genetic variants associate with HIV-1 susceptibility in Africans.

Details

Title Common human genetic variants and HIV-1 susceptibility: a genome-wide survey in a homogeneous African population
Author(s) Petrovski, Slavé ; Fellay, Jacques ; Shianna, Kevin V. ; Carpenetti, Nicole ; Kumwenda, Johnstone ; Kamanga, Gift ; Kamwendo, Deborah D. ; Letvin, Norman L. ; McMichael, Andrew J. ; Haynes, Barton F. ; Cohen, Myron S. ; Goldstein, David B.
Published in AIDS
Volume 25
Issue 4
Pages 513-8
Date 2011
DOI 10.1097/QAD.0b013e328343817b
Laboratories GR-FE
Record Appears in Scientific production and competences > SV - School of Life Sciences > GHI - Global Health Institute > GR-FE - Fellay Group
Peer-reviewed publications
Work outside EPFL
Journal Articles
Published

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