Abstract
The prototypic non-receptor tyrosine kinase c-Abl is implicated in various cellular processes. Its oncogenic counterpart, the Bcr-Abl fusion protein, causes certain human leukaemias. Recent insights into the structure and regulation of the c-Abl and Bcr-Abl tyrosine kinases have changed the way we look at these enzymes.
Details
Title
Regulation of the c-Abl and Bcr-Abl tyrosine kinases
Author(s)
Hantschel, Oliver ; Superti-Furga, Giulio
Published in
Nature reviews. Molecular cell biology
Volume
5
Issue
1
Pages
33-44
Date
2004
Publisher
Nature Publishing Group
ISSN
1471-0072
Laboratories
UPHAN
Record Appears in
Scientific production and competences > SV - School of Life Sciences > ISREC - Swiss Institute for Experimental Cancer Research > UPHAN - Prof. Hantschel Group
Peer-reviewed publications
Work outside EPFL
Published
Reviews
Peer-reviewed publications
Work outside EPFL
Published
Reviews
Record creation date
2011-03-21