Regulation of the c-Abl and Bcr-Abl tyrosine kinases

The prototypic non-receptor tyrosine kinase c-Abl is implicated in various cellular processes. Its oncogenic counterpart, the Bcr-Abl fusion protein, causes certain human leukaemias. Recent insights into the structure and regulation of the c-Abl and Bcr-Abl tyrosine kinases have changed the way we look at these enzymes.


Published in:
Nature reviews. Molecular cell biology, 5, 1, 33-44
Year:
2004
Publisher:
Nature Publishing Group
ISSN:
1471-0072
Laboratories:




 Record created 2011-03-21, last modified 2018-03-17


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