Sequential ATRA-Reductive Cyclopropanation Reactions with a Ruthenium Catalyst in the Presence of Manganese

Atom-transfer radical addition (ATRA) reactions of ethyl trichloroacetate, dichloromalononitrile, or diethyl 2,2-dichloromalonate with olefins followed by dechlorination have provided functionalized cyclopropanes in one step. The RuIII complex [Cp*RuCl2(PPh3)] was used as a catalyst precursor and commercial Mn powder as reducing agent. Reactions with the less activated substrate ethyl dichloroacetate gave ATRA products with high turnover numbers but cyclopropanation was not observed.


Published in:
European Journal of Organic Chemistry, 2272-2277
Year:
2011
Publisher:
Wiley-Blackwell
ISSN:
1434-193X
Keywords:
Laboratories:




 Record created 2011-03-10, last modified 2018-03-17

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