Photodynamic Therapy Selectively Enhances Liposomal Doxorubicin Uptake in Sarcoma Tumors to Rodent Lungs

Background: In specific conditions, photodynamic therapy (PDT) can enhance the distribution of macromolecules across the endothelial barrier in solid tumors. It was recently postulated that tumor neovessels were more responsive to PDT than the normal vasculature. We hypothesized that Visudyne (R)-mediated PDT could selectively increase liposomal doxorubicin (Liporubicin (TM)) uptake in sarcoma tumors to rodent lungs while sparing the normal surrounding tissue.


Published in:
Lasers In Surgery And Medicine, 42, 391-399
Year:
2010
Publisher:
Wiley-Blackwell
ISSN:
0196-8092
Keywords:
Laboratories:




 Record created 2011-01-27, last modified 2018-03-08


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