@article{Messori:161831, title = {Cytotoxic profile and peculiar reactivity with biomolecules of a novel “rule-breaker” iodo-platinum(II) complex}, author = {Messori, L. and Casini, Angela and Gabbiani, C. and Michelucci, E. and Cubo, L. and Ríos-Luci, C. and Padrón, J. M. and Navarro-Ranninger, C. and Quiroga, A. G.}, journal = {MedChemLetters }, volume = {1}, pages = {381–385}, year = {2010}, abstract = {Novel and surprising biological properties were disclosed for the platinum(II) complex cis-diiodidodiisopropylamineplatinum(II). Remarkably this new platinum(II) complex manifests pronounced antiproliferative properties in vitro, in some cases superior to those of cisplatin. A peculiar reactivity with the model protein cytochrome c was indeed highlighted based on the loss of amine ligands and retention of iodides.}, url = {http://infoscience.epfl.ch/record/161831}, doi = {10.1021/ml100081e}, }