000161730 001__ 161730
000161730 005__ 20180913114641.0
000161730 022__ $$a1879-1484
000161730 02470 $$2PMID$$a17324434
000161730 02470 $$2ISI$$a000250891800013
000161730 0247_ $$2doi$$a10.1016/j.atherosclerosis.2007.01.024
000161730 037__ $$aARTICLE
000161730 245__ $$aTranscriptional and post-transcriptional regulation of preproendothelin-1 by plaque-prone hemodynamics
000161730 269__ $$a2007
000161730 260__ $$c2007
000161730 336__ $$aJournal Articles
000161730 520__ $$aPlaque-prone areas are exposed to a particular hemodynamic environment characterized by a low mean shear stress value and a cyclic reversal flow. This mechanical environment, also termed oscillatory shear stress (OSS), induces the expression of several pro-atherogenic genes in the endothelial cells including the preproendothelin-1 (ppET-1) gene. The present paper investigates the molecular mechanisms of this induction.
000161730 700__ $$ada Silva, Rafaela Fernandes
000161730 700__ $$aChambaz, Céline
000161730 700__ $$0240635$$aStergiopulos, Nikos$$g106482
000161730 700__ $$aHayoz, Daniel
000161730 700__ $$aSilacci, Paolo
000161730 773__ $$j194$$k2$$q383-90$$tAtherosclerosis
000161730 909C0 $$0252351$$pLHTC$$xU11843
000161730 909CO $$ooai:infoscience.tind.io:161730$$pSTI$$particle
000161730 937__ $$aEPFL-ARTICLE-161730
000161730 973__ $$aEPFL$$rREVIEWED$$sPUBLISHED
000161730 980__ $$aARTICLE