Regulation of arginase pathway in response to wall shear stress
2009
Abstract
Alterations of wall shear stress can predispose the endothelium to the development of atherosclerotic plaques. Ample evidence indicates that arginase expression and/or activity correlates with several risk factors for cardiovascular disease including atherosclerosis. We investigated the regulation of arginase pathway in response to distinct patterns of wall shear stress.
Details
Title
Regulation of arginase pathway in response to wall shear stress
Author(s)
Thacher, Tyler N ; Gambillara, Veronica ; Riche, Fabienne ; Silacci, Paolo ; Stergiopulos, Nikos ; da Silva, Rafaela F
Published in
Atherosclerosis
Volume
210
Issue
1
Pages
63-70
Date
2009
ISSN
1879-1484
Keywords
Arginase; Nitric oxide; Hemodynamic forces; Wall shear stress; Oscillatory shear stress; Mechanotransduction; Atherosclerosis; Plaque-Prone Hemodynamics; Oxide-Mediated Dilation; Nitric-Oxide; Endothelial Dysfunction; Coronary Arterioles; Cell-Proliferation; Carotid Arteries; Smooth-Muscle; Up-Regulation; Expression
Other identifier(s)
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Laboratories
LHTC
Record Appears in
Scientific production and competences > STI - School of Engineering > IBI-STI - Interfaculty Institute of Bioengineering > LHTC - Hemodynamics and Cardiovascular Technology Laboratory
Peer-reviewed publications
Work produced at EPFL
Journal Articles
Published
Peer-reviewed publications
Work produced at EPFL
Journal Articles
Published
Record creation date
2010-12-16