Genotype-phenotype correlation of age-related macular degeneration: influence of complement factor H polymorphism
Background/aims: Complement factor H ( CFH) Y402H polymorphism shows a strong association with age-related macular degeneration (AMD). Although the phenotypic concordance of AMD has been shown in sibling/twin studies, little is known about the genotype phenotype association. In this study, we investigated whether CFH Y402H is associated with early phenotypic features.
Record created on 2010-11-30, modified on 2016-08-09