Frequency encoded assessment of retinal physiology - art. no. 684401

We demonstrate in-vivo functional imaging of the human retina with Fourier domain optical coherence tomography employing frequency encoding of an excitation pattern. The principle is based on projecting a modulated rectangular pattern across the foveal region and acquiring a time series of B-Scans at the same vertical position across the pattern. The idea is to modulate the excitation with a frequency that is distinct from the heartbeat and irregular motion artifacts. Fourier analysis of the time series at each transverse position in the B-scan series allows assessing the retinal response as change in the FDOCT reflectivity signal exactly at the pattern modulation frequency. We observe a change in retinal reflectivity within the region of the outer segment photoreceptor layer exactly at the pattern modulation frequency.

Published in:
Ophthalmic Technologies Xviii, 6844, 84401-84401
Presented at:
18th Conference on Ophthalmic Technologies, San Jose, CA, Jan 19-21, 2008
Spie-Int Soc Optical Engineering, Po Box 10, Bellingham, Wa 98227-0010 Usa

 Record created 2010-11-30, last modified 2018-01-28

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