MicroPET imaging of 5-HT1A receptors in rat brain: a test-retest [F-18]MPPF study
Purpose Earlier studies have shown that positron emission tomography (PET) imaging with the radioligand [F-18] MPPF allows for measuring the binding potential of serotonin 5-hydroxytryptamine(1A) (5-HT1A) receptors in different regions of animal and human brain, including that of 5-HT1A autoreceptors in the raphe nuclei. In the present study, we sought to determine if such data could be obtained in rat, with a microPET (R4, Concorde Microsystems).
Keywords: Binding potential ; Serotonin receptors ; Brain imaging ; Autoreceptors ; Positron emission tomography ; Positron-Emission-Tomography ; Dorsal Raphe Nucleus ; Central-Nervous-System ; In-Vivo ; Healthy-Volunteers ; Serotonin Neurons ; Beta-Microprobe ; H-3 Way-100635 ; Fluoro Analog ; F-18-Mppf Pet
Record created on 2010-11-30, modified on 2016-08-09