MicroPET imaging of 5-HT1A receptors in rat brain: a test-retest [F-18]MPPF study
Aznavour, Nicolas; Benkelfat, Chawki; Gravel, Paul; Aliaga, Antonio; Rosa-Neto, Pedro; Bedell, Barry; Zimmer, Luc; Descarries, Laurent
2009

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Abstract

Purpose Earlier studies have shown that positron emission tomography (PET) imaging with the radioligand [F-18] MPPF allows for measuring the binding potential of serotonin 5-hydroxytryptamine(1A) (5-HT1A) receptors in different regions of animal and human brain, including that of 5-HT1A autoreceptors in the raphe nuclei. In the present study, we sought to determine if such data could be obtained in rat, with a microPET (R4, Concorde Microsystems).

Details

Title MicroPET imaging of 5-HT1A receptors in rat brain: a test-retest [F-18]MPPF study
Author(s) Aznavour, Nicolas ; Benkelfat, Chawki ; Gravel, Paul ; Aliaga, Antonio ; Rosa-Neto, Pedro ; Bedell, Barry ; Zimmer, Luc ; Descarries, Laurent
Published in European Journal Of Nuclear Medicine And Molecular Imaging
Volume 36
Pages 53-62
Date 2009
Publisher Springer-Verlag
ISSN 1619-7070
Keywords
Note National Licences
DOI https://doi.org/10.1007/s00259-008-0891-1
Other identifier(s) View record in Web of Science
Laboratories LNDC
Record Appears in Peer-reviewed publications
Work produced at EPFL
Journal Articles
Published
Record creation date 2010-11-30

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