Journal article

Modeling the Gabaergic Action of Etomidate on the Thalamocortical System

BACKGROUND: We have used a computational model of the thalamocortical system to investigate the effects of a GABAergic anesthetic (etomidate) on cerebral cortical and thalamic neuronal function. We examined the effects of phasic an tonic inhibition, as well as the relative importance of anesthetic action in the thalamus and cortex.


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