B-Alkylcatecholborane-Mediated Tandem Radical Conjugated Addition-Aldol Cyclization

A one-pot procedure involving radical conjugate addition of B-alkylcatecholboranes to enones followed by intramolecular aldol reaction is reported. Application to the stereoselective synthesis of monocyclic and bicyclic products with up to four contiguous stereogenic centers is presented.


Published in:
Organic Letters, 11, 3778-3781
Year:
2009
Keywords:
Laboratories:




 Record created 2010-11-30, last modified 2018-01-28


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