X-ray ablation of hyaluronan hydrogels: Fabrication of three-dimensional microchannel networks
Weon, B. M.; Chang, S.; Yeom, J.; Hahn, S. K.; Je, J. H.; Hwu, Y.; Margaritondo, G.
2009

Abstract

We present a simple and highly versatile protocol for polymer ablation: hard x-ray irradiation makes it possible to rapidly depolymerize hyaluronan hydrogels and fabricate three-dimensional network of microchannels. Photodynamic and photochemical analyses show that x-ray irradiation directly cleaves the polymer backbone and the total dose controls the degradation kinetics. This nonthermal ablation protocol may offer opportunities for processing organic polymers and biological materials.

Details

Title X-ray ablation of hyaluronan hydrogels: Fabrication of three-dimensional microchannel networks
Author(s) Weon, B. M. ; Chang, S. ; Yeom, J. ; Hahn, S. K. ; Je, J. H. ; Hwu, Y. ; Margaritondo, G.
Published in Journal Of Applied Physics
Volume 106
Issue 5
Pages 053518
Date 2009
Publisher American Institute of Physics
ISSN 0021-8979
Keywords
DOI https://doi.org/10.1063/1.3213358
Other identifier(s) View record in Web of Science
Laboratories LPRX
CIBM
Record Appears in Scientific production and competences > SB - School of Basic Sciences > SB Archives > LPRX - X-Ray Physics Laboratory
Scientific production and competences > SB - School of Basic Sciences > CIBM - Biomedical Imaging Research Center
Peer-reviewed publications
Work produced at EPFL
Journal Articles
Published
Record creation date 2010-11-30

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