Abstract
A solution phase combinatorial synthesis of aryl piperazines 1 and 2 is described based on the S(N)Ar reaction and Schotten-Baumann acylation. The use of excess reagent is allowed and pure arylpiperazines 1 and 2 were obtained by simple acid/base washing.
Details
Title
Solution phase combinatorial synthesis of arylpiperazines
Author(s)
Neuville, Luc ; Zhu, Jieping
Published in
Tetrahedron Letters
Volume
38
Issue
23
Pages
4091-4094
Date
1997
Publisher
Elsevier
ISSN
00404039
Laboratories
LSPN
Record Appears in
Scientific production and competences > SB - School of Basic Sciences > ISIC - Institute of Chemical Sciences and Engineering > LSPN - Laboratory of synthesis and natural products
Peer-reviewed publications
Work outside EPFL
Journal Articles
Published
Peer-reviewed publications
Work outside EPFL
Journal Articles
Published
Record creation date
2010-11-25