Asymmetric total synthesis of (-)-deoxoprosophylline

Asymmetric syntheses of (-)-deoxoprosophylline from chiral L-N,N-dibenzyl serine (TBDMS) aldehyde is reported. A highly diastereoselective intramolecular reductive amination of ω-oxo amino diol is a key step of the present synthesis. © 2001 Elsevier Science Ltd.


Published in:
Tetrahedron Letters, 42, 20, 3431-3434
Year:
2001
Publisher:
Elsevier
ISSN:
00404039
Laboratories:




 Record created 2010-11-25, last modified 2018-03-17


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