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Zinc Chloride Promoted Formal Oxidative Coupling of Aromatic Aldehydes and Isocyanides to alpha -Ketoamides

Reaction of arom. aldehydes and isocyanides in the presence of N-methylhydroxyamine, acetic acid, and zinc chloride affords the aryl alpha -ketoamides, e.g. I, in moderate to good yields. [on SciFinder (R)]

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