Rapid and efficient solid phase syntheses of cyclic peptides with endocyclic biaryl ether bonds
1997
Abstract
Solid phase syntheses of the OF4949 derivs. I (R = H, CH2CONH2) and II (R1 = H, R2 = H, NH2; R1 = NH2, R2 = H) were performed via protection/deprotection of tyrosine side chains on a support, and SNAr macrocyclization reactions. [on SciFinder (R)]
Details
Title
Rapid and efficient solid phase syntheses of cyclic peptides with endocyclic biaryl ether bonds
Author(s)
Burgess, Kevin ; Lim, Dongyeol ; Bois-Choussy, Michele ; Zhu, Jieping
Published in
Tetrahedron Letters
Volume
38
Issue
19
Pages
3345-3348
Date
1997
ISSN
0040-4039
Keywords
Substitution reaction (arom.; intramol.; rapid and efficient solid phase syntheses of cyclic peptides with endocyclic biaryl ether bonds); Solid phase synthesis (peptide; rapid and efficient solid phase syntheses of cyclic peptides with endocyclic biaryl ether bonds); solid phase prepn OF4949 deriv; nucleophilic arom macrocyclization OF4949 prepn
Note
CAN 127:34501
34-3
Amino Acids, Peptides, and Proteins
Department of Chemistry,Texas A and M University, College Station,TX,USA.
Journal
written in English.
190710-91-9P Role: BYP (Byproduct), PREP (Preparation) (rapid and efficient solid phase syntheses of cyclic peptides with endocyclic biaryl ether bonds); 163395-24-2 Role: RCT (Reactant), RACT (Reactant or reagent) (rapid and efficient solid phase syntheses of cyclic peptides with endocyclic biaryl ether bonds); 107140-32-9DP (OF4949 III); 190710-87-3P; 190710-88-4P; 190710-89-5P; 190710-90-8P Role: SPN (Synthetic preparation), PREP (Preparation) (rapid and efficient solid phase syntheses of cyclic peptides with endocyclic biaryl ether bonds)
34-3
Amino Acids, Peptides, and Proteins
Department of Chemistry,Texas A and M University, College Station,TX,USA.
Journal
written in English.
190710-91-9P Role: BYP (Byproduct), PREP (Preparation) (rapid and efficient solid phase syntheses of cyclic peptides with endocyclic biaryl ether bonds); 163395-24-2 Role: RCT (Reactant), RACT (Reactant or reagent) (rapid and efficient solid phase syntheses of cyclic peptides with endocyclic biaryl ether bonds); 107140-32-9DP (OF4949 III); 190710-87-3P; 190710-88-4P; 190710-89-5P; 190710-90-8P Role: SPN (Synthetic preparation), PREP (Preparation) (rapid and efficient solid phase syntheses of cyclic peptides with endocyclic biaryl ether bonds)
Laboratories
LSPN
Record Appears in
Scientific production and competences > SB - School of Basic Sciences > ISIC - Institute of Chemical Sciences and Engineering > LSPN - Laboratory of synthesis and natural products
Peer-reviewed publications
Work outside EPFL
Journal Articles
Published
Peer-reviewed publications
Work outside EPFL
Journal Articles
Published
Record creation date
2010-11-25