Résumé
Macrocylization via formation of the aryl-alkyl ether bond was a key step in a model synthesis of 14-membered cyclopeptide alkaloids. A new chemoenzymic synthesis of chiral 2-amino-1-arylethanol was developed in the course of this study. [on SciFinder (R)]
Détails
Titre
Approach towards the total synthesis of cyclopeptide alkaloids
Auteur(s)
Laib, Taoues ; Zhu, Jieping
Publié dans
Tetrahedron Letters
Volume
39
Numéro
3/4
Pages
283-286
Date
1998
ISSN
0040-4039
Mots-clés (libres)
Peptides; Peptides Role: BPN (Biosynthetic preparation); SPN (Synthetic preparation); BIOL (Biological study); PREP (Preparation) (cyclic; alkaloidal; approach towards total synthesis of cyclopeptide alkaloids); Alkaloids; Alkaloids Role: BPN (Biosynthetic preparation); SPN (Synthetic preparation); BIOL (Biological study); PREP (Preparation) (cyclopeptidyl; approach towards total synthesis of cyclopeptide alkaloids); cyclopeptide alkaloid synthesis; arylethanolamine prepn reaction
Note
CAN 128:141009
34-3
Amino Acids, Peptides, and Proteins
Institut de Chimie des Substances Naturelles, CNRS,Gif-sur-Yvette,Fr.
Journal
written in English.
202120-58-9P; 202120-59-0P Role: BPN (Biosynthetic preparation), BIOL (Biological study), PREP (Preparation) (approach towards total synthesis of cyclopeptide alkaloids); 202120-60-3P; 202120-61-4P; 202134-17-6P; 202134-18-7P; 202134-19-8P; 202217-47-8P; 202217-48-9P; 202217-49-0P Role: BPN (Biosynthetic preparation), RCT (Reactant), SPN (Synthetic preparation), BIOL (Biological study), PREP (Preparation), RACT (Reactant or reagent) (approach towards total synthesis of cyclopeptide alkaloids); 202120-54-5P Role: BPN (Biosynthetic preparation), SPN (Synthetic preparation), BIOL (Biological study), PREP (Preparation) (approach towards total synthesis of cyclopeptide alkaloids); 202120-62-5P Role: BYP (Byproduct), PREP (Preparation) (approach towards total synthesis of cyclopeptide alkaloids); 202120-57-8P Role: PUR (Purification or recovery), RCT (Reactant), SPN (Synthetic preparation), PREP (Preparation), RACT (Reactant or reagent) (approach towards total synthesis of cyclopeptide alkaloids); 13139-15-6; 42564-51-2; 93527-55-0 Role: RCT (Reactant), RACT (Reactant or reagent) (approach towards total synthesis of cyclopeptide alkaloids); 202120-55-6P; 202120-56-7P; 202120-63-6P Role: RCT (Reactant), SPN (Synthetic preparation), PREP (Preparation), RACT (Reactant or reagent) (approach towards total synthesis of cyclopeptide alkaloids)
34-3
Amino Acids, Peptides, and Proteins
Institut de Chimie des Substances Naturelles, CNRS,Gif-sur-Yvette,Fr.
Journal
written in English.
202120-58-9P; 202120-59-0P Role: BPN (Biosynthetic preparation), BIOL (Biological study), PREP (Preparation) (approach towards total synthesis of cyclopeptide alkaloids); 202120-60-3P; 202120-61-4P; 202134-17-6P; 202134-18-7P; 202134-19-8P; 202217-47-8P; 202217-48-9P; 202217-49-0P Role: BPN (Biosynthetic preparation), RCT (Reactant), SPN (Synthetic preparation), BIOL (Biological study), PREP (Preparation), RACT (Reactant or reagent) (approach towards total synthesis of cyclopeptide alkaloids); 202120-54-5P Role: BPN (Biosynthetic preparation), SPN (Synthetic preparation), BIOL (Biological study), PREP (Preparation) (approach towards total synthesis of cyclopeptide alkaloids); 202120-62-5P Role: BYP (Byproduct), PREP (Preparation) (approach towards total synthesis of cyclopeptide alkaloids); 202120-57-8P Role: PUR (Purification or recovery), RCT (Reactant), SPN (Synthetic preparation), PREP (Preparation), RACT (Reactant or reagent) (approach towards total synthesis of cyclopeptide alkaloids); 13139-15-6; 42564-51-2; 93527-55-0 Role: RCT (Reactant), RACT (Reactant or reagent) (approach towards total synthesis of cyclopeptide alkaloids); 202120-55-6P; 202120-56-7P; 202120-63-6P Role: RCT (Reactant), SPN (Synthetic preparation), PREP (Preparation), RACT (Reactant or reagent) (approach towards total synthesis of cyclopeptide alkaloids)
Laboratoires
LSPN
Le document apparaît dans
Production scientifique et compétences > SB - Faculté des sciences de base > ISIC - Institut des sciences et ingénierie chimiques > LSPN - Laboratoire de synthèse et produits naturels
Publications validées par des pairs
Travail hors EPFL
Articles de journaux
Publié
Publications validées par des pairs
Travail hors EPFL
Articles de journaux
Publié
Date de création de la notice
2010-11-25