A high throughput synthesis of aryl triflate and aryl nonaflate promoted by a polymer supported base (PTBD)
A rapid synthesis of aryl triflate and aryl nonaflate was developed using 4-nitrophenyl triflate and 4-nitrophenyl nonaflate as perfluoroalkanesulfonyl transfer reagents in combination with polymer supported 1,5,7-triazabicyclo[4.4.0]dec-5-ene (PTBD). Simple filtration of the reaction mixt. gave the desired products in high chem. yields and purity. The unique role of PTBD as a base and side product scavenger was demonstrated. [on SciFinder (R)]
Benzene, Its Derivatives, and Condensed Benzenoid Compounds
Institut de Chimie des Substances Naturelles, CNRS,Gif-Sur-Yvette,Fr.
written in English.
90-15-3 (1-Hydroxynaphthalene); 98-54-4 (4-tert-Butylphenol); 135-19-3 (2-Hydroxynaphthalene); 150-76-5 (4-Methoxyphenol); 540-38-5 (4-Iodophenol); 576-26-1 (2,6-Dimethylphenol); 621-59-0; 2440-79-1; 5807-14-7D (1,5,7-Triazabicyclo[4.4.0]dec-5-ene); 17763-80-3 (4-Nitrophenyl triflate); 32848-23-0 (4-Nitrophenyl nonaflate); 84794-40-1; 252573-88-9 Role: RCT (Reactant), RACT (Reactant or reagent) (prepn. of aryl triflates and aryl nonaflates promoted by a polymer supported triazabicyclodecene); 3857-83-8P; 32848-17-2P; 42096-34-4P; 66107-29-7P; 86364-02-5P; 93131-74-9P; 99747-74-7P; 107658-26-4P; 109586-39-2P; 154318-75-9P; 157790-73-3P; 199465-44-6P; 247018-51-5P; 247018-52-6P; 252573-81-2P; 252573-84-5P; 252573-85-6P; 252573-86-7P; 252573-89-0P; 252573-90-3P Role: SPN (Synthetic preparation), PREP (Preparation) (prepn. of aryl triflates and aryl nonaflates promoted by a polymer supported triazabicyclodecene)
Record created on 2010-11-25, modified on 2016-08-08