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Journal article

An asymmetric total synthesis of sanjoinine G1

A convergent total synthesis of sanjoinine G1 (I), a 14-membered cyclopeptide alkaloid was described. Formation of aryl alkyl ether bond with concomitant construction of macrocycle by way of an intramol. SNAr reaction was the key step in this synthesis. Only two conventional peptide coupling steps were required for the prepn. of the cyclization precursor. [on SciFinder (R)]

    Keywords: Asymmetric synthesis and induction (asym. total synthesis of sanjoinine G1) ; asym total synthesis sanjoinine G1

    Note:

    CAN 130:209969

    34-3

    Amino Acids, Peptides, and Proteins

    Institut de Chimie des Substances Naturelles, CNRS,Gif-sur-Yvette,Fr.

    Journal

    0040-4039

    written in English.

    217495-61-9P; 221004-72-4P; 221004-77-9P Role: BYP (Byproduct), PREP (Preparation) (asym. total synthesis of sanjoinine G1); 10148-70-6 ((2S,3S)-3-Hydroxyleucine); 17469-89-5 (N,N-Dimethyl-L-phenylalanine); 221004-71-3 Role: RCT (Reactant), RACT (Reactant or reagent) (asym. total synthesis of sanjoinine G1); 87421-21-4P; 202478-35-1P; 221004-68-8P; 221004-69-9P; 221004-70-2P; 221004-73-5P; 221004-74-6P; 221004-75-7P; 221004-76-8P Role: RCT (Reactant), SPN (Synthetic preparation), PREP (Preparation), RACT (Reactant or reagent) (asym. total synthesis of sanjoinine G1); 107462-36-2P (Sanjoinine G1) Role: SPN (Synthetic preparation), PREP (Preparation) (asym. total synthesis of sanjoinine G1)

    Reference

    Record created on 2010-11-25, modified on 2016-08-08

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