Synthesis of a model 22-membered AB-C-O-D ring of vancomycin containing biaryl and biaryl ether linkages

The synthesis of a 22-membered macrocycle I with an endo aryl-aryl ether linkage and a biaryl bond related to the AB-C-O-D ring of vancomycin is described. [on SciFinder (R)]


Published in:
Tetrahedron Letters, 41, 11, 1747-1751
Year:
2000
Keywords:
Note:
CAN 133:17790
34-3
Amino Acids, Peptides, and Proteins
Institut de Chimie des Substances Naturelles, CNRS,Gif-Sur-Yvette,Fr.
Journal
0040-4039
written in English.
1404-90-6P (Vancomycin) Role: PNU (Preparation, unclassified), PREP (Preparation) (prepn. of 22-membered macrocycle fragment of vancomycin contg. biaryl and biaryl ether linkages); 621-37-4 (3-Hydroxyphenylacetic acid); 10065-72-2 (L-Alanine methyl ester); 188624-33-1; 271798-96-0 Role: RCT (Reactant), RACT (Reactant or reagent) (prepn. of 22-membered macrocycle fragment of vancomycin contg. biaryl and biaryl ether linkages); 271798-97-1P; 271798-98-2P; 271798-99-3P; 271799-00-9P; 271799-01-0P; 271799-02-1P; 271799-03-2P; 272116-69-5P; 272116-70-8P; 272116-71-9P; 272116-72-0P; 272116-73-1P; 272116-74-2P Role: RCT (Reactant), SPN (Synthetic preparation), PREP (Preparation), RACT (Reactant or reagent) (prepn. of 22-membered macrocycle fragment of vancomycin contg. biaryl and biaryl ether linkages); 272116-75-3P; 272116-76-4P; 272116-77-5P Role: SPN (Synthetic preparation), PREP (Preparation) (prepn. of 22-membered macrocycle fragment of vancomycin contg. biaryl and biaryl ether linkages)
Laboratories:




 Record created 2010-11-25, last modified 2018-09-13


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