Total synthesis of horsfiline: a palladium-catalyzed domino Heck-cyanation strategy
2009
Résumé
A total synthesis of horsfiline (I) has been accomplished featuring a key intramol. palladium-catalyzed domino Heck-cyanation sequence for the formation of the 3,3'-disubstituted oxindole. [on SciFinder (R)]
Détails
Titre
Total synthesis of horsfiline: a palladium-catalyzed domino Heck-cyanation strategy
Auteur(s)
Jaegli, Stephanie ; Vors, Jean-Pierre ; Neuville, Luc ; Zhu, Jieping
Publié dans
Synlett
Numéro
18
Pages
2997-2999
Date
2009
ISSN
0936-5214
Mots-clés (libres)
Note
CAN 152:192342
31-5
Alkaloids
Institut de Chimie des Substances Naturelles,CNRS,Gif-sur-Yvette,Fr.
written in English.
1206487-06-0P Role: BYP (Byproduct), PREP (Preparation) (total synthesis of horsfiline via palladium-catalyzed domino intramol. Heck-cyanation); 3375-31-3 Role: CAT (Catalyst use), USES (Uses) (total synthesis of horsfiline via palladium-catalyzed domino intramol. Heck-cyanation); 104-94-9 (p-Anisidine); 867-13-0 (Triethyl phosphonoacetate); 13746-66-2 (Potassium ferricyanate) Role: RCT (Reactant), RACT (Reactant or reagent) (total synthesis of horsfiline via palladium-catalyzed domino intramol. Heck-cyanation); 10029-04-6P; 18437-68-8P; 146309-33-3P; 191348-14-8P; 862885-10-7P; 862885-19-6P; 900254-92-4P; 1206487-00-4P; 1206487-02-6P; 1206487-04-8P; 1206487-08-2P; 1206487-10-6P; 1206487-14-0P Role: RCT (Reactant), SPN (Synthetic preparation), PREP (Preparation), RACT (Reactant or reagent) (total synthesis of horsfiline via palladium-catalyzed domino intramol. Heck-cyanation); 136316-07-9P ((+-)-Horsfiline) Role: SPN (Synthetic preparation), PREP (Preparation) (total synthesis of horsfiline via palladium-catalyzed domino intramol. Heck-cyanation)
31-5
Alkaloids
Institut de Chimie des Substances Naturelles,CNRS,Gif-sur-Yvette,Fr.
written in English.
1206487-06-0P Role: BYP (Byproduct), PREP (Preparation) (total synthesis of horsfiline via palladium-catalyzed domino intramol. Heck-cyanation); 3375-31-3 Role: CAT (Catalyst use), USES (Uses) (total synthesis of horsfiline via palladium-catalyzed domino intramol. Heck-cyanation); 104-94-9 (p-Anisidine); 867-13-0 (Triethyl phosphonoacetate); 13746-66-2 (Potassium ferricyanate) Role: RCT (Reactant), RACT (Reactant or reagent) (total synthesis of horsfiline via palladium-catalyzed domino intramol. Heck-cyanation); 10029-04-6P; 18437-68-8P; 146309-33-3P; 191348-14-8P; 862885-10-7P; 862885-19-6P; 900254-92-4P; 1206487-00-4P; 1206487-02-6P; 1206487-04-8P; 1206487-08-2P; 1206487-10-6P; 1206487-14-0P Role: RCT (Reactant), SPN (Synthetic preparation), PREP (Preparation), RACT (Reactant or reagent) (total synthesis of horsfiline via palladium-catalyzed domino intramol. Heck-cyanation); 136316-07-9P ((+-)-Horsfiline) Role: SPN (Synthetic preparation), PREP (Preparation) (total synthesis of horsfiline via palladium-catalyzed domino intramol. Heck-cyanation)
Laboratoires
LSPN
Le document apparaît dans
Production scientifique et compétences > SB - Faculté des sciences de base > ISIC - Institut des sciences et ingénierie chimiques > LSPN - Laboratoire de synthèse et produits naturels
Publications validées par des pairs
Travail hors EPFL
Articles de journaux
Publié
Publications validées par des pairs
Travail hors EPFL
Articles de journaux
Publié
Date de création de la notice
2010-11-25