000154701 001__ 154701
000154701 005__ 20180913060058.0
000154701 022__ $$a0959-440X
000154701 037__ $$aARTICLE
000154701 245__ $$aSearching for regulatory elements in human noncoding sequences
000154701 260__ $$bElsevier$$c1997
000154701 269__ $$a1997
000154701 336__ $$aReviews
000154701 520__ $$aImportant progress has been made in the past two years in the identification of Pol II promoters. For most other regulatory elements, however, current biological knowledge is still insufficient to allow the development of prediction tools. The phylogenetic-footprinting strategy, which is based on the comparative analysis of homologous sequences, is a very efficient approach to identify new unknown regulatory elements. The recent organization of large-scale sequencing projects for some model vertebrate organisms will be extremely valuable for the prediction of regulatory elements in the human genome.
000154701 6531_ $$aModels, Biological
000154701 6531_ $$aPhylogeny
000154701 6531_ $$aRegulatory Sequences, Nucleic Acid
000154701 700__ $$aDuret, L.
000154701 700__ $$0244404$$aBucher, Philipp$$g113607
000154701 773__ $$j7$$k3$$q399-406$$tCurrent opinion in structural biology
000154701 909C0 $$0252244$$pGR-BUCHER$$xU11780
000154701 909CO $$ooai:infoscience.tind.io:154701$$pSV$$preview
000154701 917Z8 $$x182396
000154701 937__ $$aEPFL-REVIEW-154701
000154701 973__ $$aOTHER$$rREVIEWED$$sPUBLISHED
000154701 980__ $$aREVIEW