The effect of NaF in vitro on the mechanical and material properties of trabecular and cortical bone
2009
Résumé
High doses of sodium fluoride in bones lead to severe softening, by weakening interfacial properties between the inorg. minerals and the org. components, while leaving mineralization unchanged. This leads to redn. of microdamage and assocd. stress-whitening pointing to a change in failure mode. Accordingly, elastic modulus, failure stress, and indentation-distance increase are decreased, whereas failure strain is increased. [on SciFinder (R)]
Détails
Titre
The effect of NaF in vitro on the mechanical and material properties of trabecular and cortical bone
Auteur(s)
Thurner, Philipp J. ; Erickson, Blake ; Turner, Patricia ; Jungmann, Ralf ; Lelujian, Jason ; Proctor, Alexander ; Weaver, James C. ; Schitter, Georg ; Morse, Daniel E. ; Hansma, Paul K.
Publié dans
Advanced Materials
Volume
21
Numéro
4
Pages
451-457
Date
2009
ISSN
0935-9648
Mots-clés (libres)
Bone (cortical; effect of sodium fluoride in vitro on mech. and material properties of trabecular and cortical bone); Human; Osteoporosis (effect of sodium fluoride in vitro on mech. and material properties of trabecular and cortical bone); Bone (trabecula; effect of sodium fluoride in vitro on mech. and material properties of trabecular and cortical bone); sodium fluoride trabecular cortical bone osteoporosis
Note
CAN 150:366841
1-12
Pharmacology
Bioengineering Science Research Group, School of Engineering Science,University of Southampton,Highfield, Southampton,UK.
Journal
7681-49-4 (Sodium fluoride) Role: ADV (Adverse effect, including toxicity), PAC (Pharmacological activity), THU (Therapeutic use), BIOL (Biological study), USES (Uses) (effect of sodium fluoride in vitro on mech. and material properties of trabecular and cortical bone)
1-12
Pharmacology
Bioengineering Science Research Group, School of Engineering Science,University of Southampton,Highfield, Southampton,UK.
Journal
7681-49-4 (Sodium fluoride) Role: ADV (Adverse effect, including toxicity), PAC (Pharmacological activity), THU (Therapeutic use), BIOL (Biological study), USES (Uses) (effect of sodium fluoride in vitro on mech. and material properties of trabecular and cortical bone)
Laboratoires
LBNI
Le document apparaît dans
Production scientifique et compétences > STI - Faculté des sciences et techniques de l'ingénieur > IBI-STI - Institut Interfacultaire de Bioingénierie > LBNI - Laboratoire de bio- et nano-instrumentation
Publications validées par des pairs
Travail hors EPFL
Articles de journaux
Publié
Publications validées par des pairs
Travail hors EPFL
Articles de journaux
Publié
Date de création de la notice
2010-11-05