000151372 001__ 151372
000151372 005__ 20181203022000.0
000151372 022__ $$a0026-8925
000151372 02470 $$2PMID$$a6092858
000151372 0247_ $$2doi$$a10.1007/BF00332766
000151372 037__ $$aARTICLE
000151372 245__ $$aDNA sequence analysis of the Serratia marcescens ompA gene: implications for the organisation of an enterobacterial outer membrane protein
000151372 269__ $$a1984
000151372 260__ $$c1984
000151372 336__ $$aJournal Articles
000151372 520__ $$aThe cloned ompA gene from Serratia marcescens was fully expressed in Escherichia coli and its product correctly assembled into the outer membrane. The S. marcescens polypeptide was not functionally equivalent to the E. coli OmpA protein, which serves as a phage receptor and as a component of several colicin uptake systems. DNA sequence analysis of the gene showed that three regions of the protein likely to be exposed on the cell surface not only differed extensively from the corresponding regions of the E. coli polypeptide but also from all other sequenced OmpA proteins. It is suggested that this sequence polymorphism represents a safety mechanism by which the various enterobacterial species can avoid cross-infection by noxious agents such as phages or colicins.
000151372 6531_ $$aGenes
000151372 6531_ $$aGenes, Bacterial
000151372 700__ $$aBraun, G
000151372 700__ $$g177247$$aCole, S T$$0243892
000151372 773__ $$j195$$tMolecular & general genetics : MGG$$k1-2$$q321-8
000151372 909C0 $$xU11742$$0252302$$pUPCOL
000151372 909CO $$pSV$$particle$$ooai:infoscience.tind.io:151372
000151372 937__ $$aEPFL-ARTICLE-151372
000151372 973__ $$rREVIEWED$$sPUBLISHED$$aOTHER
000151372 980__ $$aARTICLE