Novel mutation in 16S rRNA associated with streptomycin dependence in Mycobacterium tuberculosis.

Molecular characterization of a streptomycin-dependent mutant of Mycobacterium tuberculosis revealed the presence of a novel mutation in the rrs gene encoding 16S rRNA. Insertion of an additional cytosine in the 530 loop of 16S rRNA, a region known to be involved in streptomycin susceptibility and resistance, was associated with streptomycin dependence.


Published in:
Antimicrobial agents and chemotherapy, 39, 3, 769-770
Year:
1995
ISSN:
0066-4804
Other identifiers:
Laboratories:




 Record created 2010-09-07, last modified 2018-12-03


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